The role of histone modification in DNA double-strand break repair in Schizosaccharomyces pombe
<p>DNA double-strand breaks (DSBs) are highly genotoxic lesions, which when incorrectly repaired can lead to gross chromosomal rearrangements and tumourigenesis through oncogene activation or loss of heterozygosity at tumour suppressor loci. Chromatin structure and therefore histone modificati...
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| Format: | Thesis |
| Language: | English |
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2012
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