Pericardial and porcine stentless aortic valves: are they hemodynamically different?
BACKGROUND: We sought to compare the early hemodynamic performance of pericardial stentless aortic valves with that of well-established porcine stentless aortic prostheses. METHODS: A total of 169 patients (97 men and 72 women, aged 73+/-6 years) undergoing aortic valve replacement received either a...
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| Format: | Conference item |
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2001
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| author | Jin, X Westaby, S |
| author_facet | Jin, X Westaby, S |
| author_sort | Jin, X |
| collection | OXFORD |
| description | BACKGROUND: We sought to compare the early hemodynamic performance of pericardial stentless aortic valves with that of well-established porcine stentless aortic prostheses. METHODS: A total of 169 patients (97 men and 72 women, aged 73+/-6 years) undergoing aortic valve replacement received either a pericardial (Pericarbon, Sorin Biomedica, Saluggia, Italy; n = 89) or a porcine (Freestyle, Medtronic, n = 80) stentless aortic valve. Aortic valve hemodynamics and root dynamism were assessed by Doppler echocardiography at discharge and 12 months after implantation. RESULTS: Clinical demographic data, valve size (24.0+/-1.9 vs 24.6+/-2.3 mm), and body surface area (1.85+/-0.19 vs 1.80+/-0.19 m2) did not differ between porcine and pericardial valves (both p > 0.05). The 1-year postoperative mean valve pressure gradient (4.2+/-2.6 vs 3.7+/-2.6 mm Hg), effective orifice area (2.2+/-0.8 vs 2.2+/-0.8 cm2), and left ventricular ejection fraction (62+/-13 vs 63+/-13, %) also did not differ (all p > 0.05). However, at discharge, systolic increase in aortic sinus diameter was significantly greater in pericardial valves than in porcine ones (7.7+/-5.7 vs 4.9%+/-4.2%, p < 0.01). Furthermore, pericardial valves had a greater slope of effective orifice area-systolic aortic flow relationship (0.89+/-0.07 vs 0.70+/-0.06, cm2/100 mL/s, p < 0.01). CONCLUSIONS: Nonprosthetic thin-walled pericardial valves appear to offer better aortic root dynamism and more efficient hemodynamics than those of porcine valves immediately after implant. At 1-year follow-up, however, both types of stentless valves provide equally excellent hemodynamics. The clinical choice between the two will depend on their long-term durability. |
| first_indexed | 2024-03-07T00:57:41Z |
| format | Conference item |
| id | oxford-uuid:88a4552e-09b9-4361-ac9a-847c80eb4007 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T00:57:41Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:88a4552e-09b9-4361-ac9a-847c80eb40072022-03-26T22:18:46ZPericardial and porcine stentless aortic valves: are they hemodynamically different?Conference itemhttp://purl.org/coar/resource_type/c_5794uuid:88a4552e-09b9-4361-ac9a-847c80eb4007Symplectic Elements at Oxford2001Jin, XWestaby, SBACKGROUND: We sought to compare the early hemodynamic performance of pericardial stentless aortic valves with that of well-established porcine stentless aortic prostheses. METHODS: A total of 169 patients (97 men and 72 women, aged 73+/-6 years) undergoing aortic valve replacement received either a pericardial (Pericarbon, Sorin Biomedica, Saluggia, Italy; n = 89) or a porcine (Freestyle, Medtronic, n = 80) stentless aortic valve. Aortic valve hemodynamics and root dynamism were assessed by Doppler echocardiography at discharge and 12 months after implantation. RESULTS: Clinical demographic data, valve size (24.0+/-1.9 vs 24.6+/-2.3 mm), and body surface area (1.85+/-0.19 vs 1.80+/-0.19 m2) did not differ between porcine and pericardial valves (both p > 0.05). The 1-year postoperative mean valve pressure gradient (4.2+/-2.6 vs 3.7+/-2.6 mm Hg), effective orifice area (2.2+/-0.8 vs 2.2+/-0.8 cm2), and left ventricular ejection fraction (62+/-13 vs 63+/-13, %) also did not differ (all p > 0.05). However, at discharge, systolic increase in aortic sinus diameter was significantly greater in pericardial valves than in porcine ones (7.7+/-5.7 vs 4.9%+/-4.2%, p < 0.01). Furthermore, pericardial valves had a greater slope of effective orifice area-systolic aortic flow relationship (0.89+/-0.07 vs 0.70+/-0.06, cm2/100 mL/s, p < 0.01). CONCLUSIONS: Nonprosthetic thin-walled pericardial valves appear to offer better aortic root dynamism and more efficient hemodynamics than those of porcine valves immediately after implant. At 1-year follow-up, however, both types of stentless valves provide equally excellent hemodynamics. The clinical choice between the two will depend on their long-term durability. |
| spellingShingle | Jin, X Westaby, S Pericardial and porcine stentless aortic valves: are they hemodynamically different? |
| title | Pericardial and porcine stentless aortic valves: are they hemodynamically different? |
| title_full | Pericardial and porcine stentless aortic valves: are they hemodynamically different? |
| title_fullStr | Pericardial and porcine stentless aortic valves: are they hemodynamically different? |
| title_full_unstemmed | Pericardial and porcine stentless aortic valves: are they hemodynamically different? |
| title_short | Pericardial and porcine stentless aortic valves: are they hemodynamically different? |
| title_sort | pericardial and porcine stentless aortic valves are they hemodynamically different |
| work_keys_str_mv | AT jinx pericardialandporcinestentlessaorticvalvesaretheyhemodynamicallydifferent AT westabys pericardialandporcinestentlessaorticvalvesaretheyhemodynamicallydifferent |