Whole-genome methylation analysis of benign and malignant colorectal tumours.

Changes in DNA methylation, whether hypo- or hypermethylation, have been shown to be associated with the progression of colorectal cancer. Methylation changes substantially in the progression from normal mucosa to adenoma and to carcinoma. This phenomenon has not been studied extensively and studies...

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Detalhes bibliográficos
Main Authors: Beggs, A, Jones, A, El-Bahrawy, M, El-Bahwary, M, Abulafi, M, Hodgson, S, Tomlinson, I
Formato: Journal article
Idioma:English
Publicado em: 2013