The intrinsic flexibility of the Kv voltage sensor and its implications for channel gating.
Analysis of the crystal structures of the intact voltage-sensitive potassium channel KvAP (from Aeropyrum pernix) and Kv1.2 (from rat brain), along with the isolated voltage sensor (VS) domain from KvAP, raises the question of the exact nature of the voltage-sensing conformational change that trigge...
Main Authors: | Sands, Z, Grottesi, A, Sansom, MS |
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Format: | Journal article |
Language: | English |
Published: |
2006
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