Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study.

Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study.

Mutations in the WNK1 gene cause Gordon's syndrome, a rare Mendelian form of hypertension. We assessed whether common WNK1 variants might also contribute to essential hypertension (EH), a multifactorial disorder affecting > 25% of the adult population worldwide. A panel of 19 single nucl...

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Main Authors: Newhouse, S, Wallace, C, Dobson, R, Mein, C, Pembroke, J, Farrall, M, Clayton, D, Brown, M, Samani, N, Dominiczak, A, Connell, J, Webster, J, Lathrop, G, Caulfield, M, Munroe, P
格式: Journal article
語言:English
出版: 2005

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