Plagiarizing plants: amino sugars as a class of glycosidase inhibitors.
Many polyhydroxylated alkaloids from plants are specific inhibitors of glycosidases. Information about these has led to the development of a wide range of both naturally occurring and synthetic inhibitors which may be used for mechanistic studies and for the purification of these enzymes. Sugar lact...
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Fformat: | Journal article |
Iaith: | English |
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1990
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author | Fleet, G Fellows, L Winchester, B |
author_facet | Fleet, G Fellows, L Winchester, B |
author_sort | Fleet, G |
collection | OXFORD |
description | Many polyhydroxylated alkaloids from plants are specific inhibitors of glycosidases. Information about these has led to the development of a wide range of both naturally occurring and synthetic inhibitors which may be used for mechanistic studies and for the purification of these enzymes. Sugar lactones are starting materials for highly efficient syntheses of deoxymannojirimycin and deoxyfuconojirimycin and of a number of their iminoheptitol analogues. This has allowed an investigation of the relationship between mannosidase and fucosidase inhibition. |
first_indexed | 2024-03-07T01:00:33Z |
format | Journal article |
id | oxford-uuid:89916a80-5aa1-41cd-87dd-2b5fa60322c0 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T01:00:33Z |
publishDate | 1990 |
record_format | dspace |
spelling | oxford-uuid:89916a80-5aa1-41cd-87dd-2b5fa60322c02022-03-26T22:25:28ZPlagiarizing plants: amino sugars as a class of glycosidase inhibitors.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:89916a80-5aa1-41cd-87dd-2b5fa60322c0EnglishSymplectic Elements at Oxford1990Fleet, GFellows, LWinchester, BMany polyhydroxylated alkaloids from plants are specific inhibitors of glycosidases. Information about these has led to the development of a wide range of both naturally occurring and synthetic inhibitors which may be used for mechanistic studies and for the purification of these enzymes. Sugar lactones are starting materials for highly efficient syntheses of deoxymannojirimycin and deoxyfuconojirimycin and of a number of their iminoheptitol analogues. This has allowed an investigation of the relationship between mannosidase and fucosidase inhibition. |
spellingShingle | Fleet, G Fellows, L Winchester, B Plagiarizing plants: amino sugars as a class of glycosidase inhibitors. |
title | Plagiarizing plants: amino sugars as a class of glycosidase inhibitors. |
title_full | Plagiarizing plants: amino sugars as a class of glycosidase inhibitors. |
title_fullStr | Plagiarizing plants: amino sugars as a class of glycosidase inhibitors. |
title_full_unstemmed | Plagiarizing plants: amino sugars as a class of glycosidase inhibitors. |
title_short | Plagiarizing plants: amino sugars as a class of glycosidase inhibitors. |
title_sort | plagiarizing plants amino sugars as a class of glycosidase inhibitors |
work_keys_str_mv | AT fleetg plagiarizingplantsaminosugarsasaclassofglycosidaseinhibitors AT fellowsl plagiarizingplantsaminosugarsasaclassofglycosidaseinhibitors AT winchesterb plagiarizingplantsaminosugarsasaclassofglycosidaseinhibitors |