Evidence from single nucleotide polymorphism analyses of ADVANCE study demonstrates EFNB3 as a hypertension risk gene

EPH kinases and their ligands, ephrins (EFNs), have vital and diverse biological functions. We recently reported that Efnb3 gene deletion results in hypertension in female but not male mice. These data suggest that EFNB3 regulates blood pressure in a sex- and sex hormone-dependent way. In the presen...

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Main Authors: Tremblay, J, Wang, Y, Raelson, J, Marois-Blanchet, F, Wu, Z, Luo, H, Bradley, E, Chalmers, J, Woodward, M, Harrap, S, Hamet, P, Wu, J
格式: Journal article
出版: Springer Nature 2017