Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells.

Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells.

We have obtained transgenic mice in which an erythropoietin-SV40 virus T antigen fusion gene is homologously recombined into the native Epo locus. This gene is expressed in a tissue-specific manner closely resembling that of the native Epo gene. Immunohistochemical detection of SV40 T antigen has be...

書目詳細資料
Main Authors:	Maxwell, P, Ferguson, D, Osmond, M, Pugh, C, Heryet, A, Doe, BG, Johnson, M, Ratcliffe, P
格式:	Journal article
語言:	English
出版:	1994

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