Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells.

We have obtained transgenic mice in which an erythropoietin-SV40 virus T antigen fusion gene is homologously recombined into the native Epo locus. This gene is expressed in a tissue-specific manner closely resembling that of the native Epo gene. Immunohistochemical detection of SV40 T antigen has be...

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Những tác giả chính: Maxwell, P, Ferguson, D, Osmond, M, Pugh, C, Heryet, A, Doe, BG, Johnson, M, Ratcliffe, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1994