Chromosomal localization of murine interleukin-1 alpha and beta genes.
DNA analyses of mouse X Chinese hamster somatic cell hybrids and of recombinant inbred mouse strains have previously shown that the interleukin-1 alpha and beta genes are tightly linked on murine chromosome 2, approximately 4.7 cM distal to beta-2-microglobulin. In this study, using in situ chromoso...
Hoofdauteurs: | , , , |
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Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
1989
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_version_ | 1826283572407828480 |
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author | Boultwood, J Breckon, G Birch, D Cox, R |
author_facet | Boultwood, J Breckon, G Birch, D Cox, R |
author_sort | Boultwood, J |
collection | OXFORD |
description | DNA analyses of mouse X Chinese hamster somatic cell hybrids and of recombinant inbred mouse strains have previously shown that the interleukin-1 alpha and beta genes are tightly linked on murine chromosome 2, approximately 4.7 cM distal to beta-2-microglobulin. In this study, using in situ chromosome hybridization, we show that the two interleukin-1 genes are located in the F region of murine chromosome 2 and discuss this physical map position in relation to conserved genetic linkage groups. |
first_indexed | 2024-03-07T01:00:53Z |
format | Journal article |
id | oxford-uuid:89aaf34b-6afb-4dca-9ed1-4f75bcb1adf6 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T01:00:53Z |
publishDate | 1989 |
record_format | dspace |
spelling | oxford-uuid:89aaf34b-6afb-4dca-9ed1-4f75bcb1adf62022-03-26T22:26:19ZChromosomal localization of murine interleukin-1 alpha and beta genes.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:89aaf34b-6afb-4dca-9ed1-4f75bcb1adf6EnglishSymplectic Elements at Oxford1989Boultwood, JBreckon, GBirch, DCox, RDNA analyses of mouse X Chinese hamster somatic cell hybrids and of recombinant inbred mouse strains have previously shown that the interleukin-1 alpha and beta genes are tightly linked on murine chromosome 2, approximately 4.7 cM distal to beta-2-microglobulin. In this study, using in situ chromosome hybridization, we show that the two interleukin-1 genes are located in the F region of murine chromosome 2 and discuss this physical map position in relation to conserved genetic linkage groups. |
spellingShingle | Boultwood, J Breckon, G Birch, D Cox, R Chromosomal localization of murine interleukin-1 alpha and beta genes. |
title | Chromosomal localization of murine interleukin-1 alpha and beta genes. |
title_full | Chromosomal localization of murine interleukin-1 alpha and beta genes. |
title_fullStr | Chromosomal localization of murine interleukin-1 alpha and beta genes. |
title_full_unstemmed | Chromosomal localization of murine interleukin-1 alpha and beta genes. |
title_short | Chromosomal localization of murine interleukin-1 alpha and beta genes. |
title_sort | chromosomal localization of murine interleukin 1 alpha and beta genes |
work_keys_str_mv | AT boultwoodj chromosomallocalizationofmurineinterleukin1alphaandbetagenes AT breckong chromosomallocalizationofmurineinterleukin1alphaandbetagenes AT birchd chromosomallocalizationofmurineinterleukin1alphaandbetagenes AT coxr chromosomallocalizationofmurineinterleukin1alphaandbetagenes |