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The Role of Active Site Threon...
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The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates
Dades bibliogràfiques
Autors principals:
Dunford, J
,
Pilka, E
,
Kwaasi, A
,
Evdokimov, A
,
Barnett, B
,
Oppermann, U
,
Ebetino, F
,
Russell, R
,
Kavanagh, K
Format:
Conference item
Publicat:
2008
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Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
per: Kwassi, A, et al.
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Interaction of the active site threonine 201 sidechain with the nitrogen of nttrogen-containing bisphosphonates is not essential for slow tight inhibition to farnesyl pyrophosphate synthase
per: Dunford, J, et al.
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The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates
per: Dunford, J, et al.
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The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants
per: Tsoumpra, MK, et al.
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The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
per: Tsoumpra, M, et al.
Publicat: (2015)