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The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates

The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates

书目详细资料
Main Authors: Dunford, J, Pilka, E, Kwaasi, A, Evdokimov, A, Barnett, B, Oppermann, U, Ebetino, F, Russell, R, Kavanagh, K
格式: Conference item
出版: 2008
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  • Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
    由: Kwassi, A, et al.
    出版: (2009)
  • Interaction of the active site threonine 201 sidechain with the nitrogen of nttrogen-containing bisphosphonates is not essential for slow tight inhibition to farnesyl pyrophosphate synthase
    由: Dunford, J, et al.
    出版: (2008)
  • The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates
    由: Dunford, J, et al.
    出版: (2008)
  • The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants
    由: Tsoumpra, MK, et al.
    出版: (2015)
  • The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
    由: Tsoumpra, M, et al.
    出版: (2015)

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