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The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates

The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates

Bibliografiske detaljer
Main Authors: Dunford, J, Pilka, E, Kwaasi, A, Evdokimov, A, Barnett, B, Oppermann, U, Ebetino, F, Russell, R, Kavanagh, K
Format: Conference item
Udgivet: 2008
  • Beholdninger
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  • Lignende værker
  • Medarbejdervisning

Lignende værker

  • Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
    af: Kwassi, A, et al.
    Udgivet: (2009)
  • Interaction of the active site threonine 201 sidechain with the nitrogen of nttrogen-containing bisphosphonates is not essential for slow tight inhibition to farnesyl pyrophosphate synthase
    af: Dunford, J, et al.
    Udgivet: (2008)
  • The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates
    af: Dunford, J, et al.
    Udgivet: (2008)
  • The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants
    af: Tsoumpra, MK, et al.
    Udgivet: (2015)
  • The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
    af: Tsoumpra, M, et al.
    Udgivet: (2015)

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