The Role of Active Site Threonine 201 in the Inhibition of Farnesyl Pyrophosphate Synthase by Nitrogen Containing Bisphosphonates

Míreanna comhchosúla

• Evidence for the involvement of the threonine 201 side-chain in the interaction of nitrogen-containing bisphosphonates with farnesyl pyrophosphate synthase
  de réir: Kwassi, A, et al.
  Foilsithe / Cruthaithe: (2009)
• Interaction of the active site threonine 201 sidechain with the nitrogen of nttrogen-containing bisphosphonates is not essential for slow tight inhibition to farnesyl pyrophosphate synthase
  de réir: Dunford, J, et al.
  Foilsithe / Cruthaithe: (2008)
• The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates
  de réir: Dunford, J, et al.
  Foilsithe / Cruthaithe: (2008)
• The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants
  de réir: Tsoumpra, MK, et al.
  Foilsithe / Cruthaithe: (2015)
• The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants.
  de réir: Tsoumpra, M, et al.
  Foilsithe / Cruthaithe: (2015)