Biophysical techniques for distinguishing ligand binding modes in cytochrome P450 monooxygenases

Biophysical techniques for distinguishing ligand binding modes in cytochrome P450 monooxygenases

The cytochrome P450 superfamily of heme monooxygenases catalyzes important chemical reactions across nature. The changes in the optical spectra of these enzymes, induced by the addition of substrates or inhibitors, are critical for assessing how these molecules bind to the P450, enhancing or inhibit...

Полное описание

Библиографические подробности
Главные авторы:	Podgorski, MN, Harbort, JS, Coleman, T, Stok, JE, Yorke, JA, Wong. L-L, Bruning, JB, Bernhardt, PV, De Voss, JJ, Harmer, JR, Bell, SG
Формат:	Journal article
Язык:	English
Опубликовано:	American Chemical Society 2020

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