Bisintercalators of DNA with a rigid linker in an extended configuration.
A new class of DNA bisintercalators is reported in which phenanthridinium or acridinium rings are connected by rigid and extended linkers of varied length. Cross-linking of DNA by bisintercalation is inferred from the unwinding and folding of linear DNA induced by the compound; after ligation and re...
Main Authors: | Mullins, S, Annan, N, Cook, P, Lowe, G |
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Format: | Journal article |
Language: | English |
Published: |
1992
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