Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters

Biotin is an essential vitamin in plants and mammals, functioning as the carbon dioxide carrier within central lipid metabolism. Bacterial pimeloyl-CoA synthetase (BioW) acts as a highly specific substrate-selection gate, ensuring the integrity of the carbon chain in biotin synthesis. BioW catalyzes...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Wang, M, Moynié, L, Harrison, P, Kelly, V, Piper, A, Naismith, J, Campopiano, D
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Springer Nature 2017