P667Impaired chronic hypoxic response in type 2 diabetic hearts is associated with inability to downregulate PPARa.

P667Impaired chronic hypoxic response in type 2 diabetic hearts is associated with inability to downregulate PPARa.

Cardiovascular disease is the leading cause of mortality in type 2 diabetic patients. Metabolic changes and abnormal hypoxia signalling in the diabetic heart are hypothesised to decrease recovery following a myocardial infarction. Therefore the aim of this study was to investigate the cardiac metabo...

Full description

Bibliographic Details
Main Authors:	Mansor, L, Carr, C, Le Page, L, Lund, T, Aasum, E, Clarke, K, Tyler, D, Heather, L
Format:	Journal article
Language:	English
Published:	2014

Similar Items

HYPOXIC PRECONDITIONING OF CARDIOSPHERE-DERIVED CELLS TO INCREASE RETENTION IN THE INFARCTED HEART
by: Tan, S, et al.
Published: (2010)

Aberrant methylation and downregulation of ZNF667-AS1 and ZNF667 promote the malignant progression of laryngeal squamous cell carcinoma
by: Wenxia Meng, et al.
Published: (2019-01-01)

IMPAIRED METABOLIC AND FUNCTIONAL ADAPTATION TO HYPOXIA IN THE TYPE 2 DIABETIC HEART
by: Mansor, L, et al.
Published: (2013)

Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation.
by: Mansor, L, et al.
Published: (2015)

Control of cardiac uncoupling proteins: PPARa-dependence?
by: Murray, A, et al.
Published: (2005)

Genetic Variability of RXRB, PPARA, and PPARG in Wegener's Granulomatosis
by: Stefan Wieczorek, et al.
Published: (2009-01-01)

Mechanism of Action of the Plateau-Adapted Gene PPARA in COPD
by: Honge Li, et al.
Published: (2024-02-01)

Induction of Glutathione Synthesis Provides Cardioprotection Regulating NO, AMPK and PPARa Signaling in Ischemic Rat Hearts
by: Yulia V. Goshovska, et al.
Published: (2021-06-01)

On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
by: Cole, M, et al.
Published: (2016)

The Inability of Language: A Rhetorical Deconstructive Analysis of Heart of Darkness
by: Li TANG
Published: (2014-10-01)

Significance of PPARA as a Treatment Target for Chronic Lymphocytic Leukemia
by: Xixi Xiang, et al.
Published: (2023-01-01)

MicroRNA-141 represses HBV replication by targeting PPARA.
by: Wei Hu, et al.
Published: (2012-01-01)

Impaired metabolic and functional recovery of the type 2 diabetic heart following hypoxia
by: Mansor, L, et al.
Published: (2013)

Correction: MicroRNA-141 Represses HBV Replication by Targeting PPARA
Published: (2012-01-01)

Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation
by: Daisuke Aibara, et al.
Published: (2022-05-01)

Correction: MicroRNA-141 Represses HBV Replication by Targeting PPARA.
by: Wei Hu, et al.
Published: (2012-01-01)

Mathematical ability, inability and disability.
by: Nelson, Michael Hugh
Published: (2005)

Is Bail-in Debt Bail-inable?
by: HWANG, SUNJOO
Published: (2019-11-01)

Inability of Physicians and Nurses to Predict Patient Satisfaction in the Emergency Department
by: Matthew C. DeLaney, et al.
Published: (2015-12-01)

Inability to Ventilate after Tube Exchange Postoperative to Pneumonectomy
by: S. E. Verstraeten, et al.
Published: (2012-01-01)

Chinese yellow cattle PPARA gene: Analyses of expression, polymorphism and trait association
by: Ningbo Chen, et al.
Published: (2018-12-01)

PPARA intron polymorphism associated with power performance in 30-s anaerobic Wingate Test.
by: Miroslav Petr, et al.
Published: (2014-01-01)

Case report: A Boy with an inability to walk; do not forget about scurvy
by: Noor Emilia Emira Mansor, et al.
Published: (2024-05-01)

An Inability to Exclude Visual Noise in Migraine
by: Tibber, MS, et al.
Published: (2014)

Ability, inability, disability, and antidiscrimination law
by: Dimitris Michailakis
Published: (2009-07-01)

The Rebellion and the inability to communicate Social Consciousness
by: Dario Terzić
Published: (2020-09-01)

Infant with inability to abduct left eye
by: Joshua K. Dodderer, et al.
Published: (2021-02-01)

Novel MRI method to detect altered left ventricular ejection and filling patterns in rodent models of disease.
by: Stuckey, D, et al.
Published: (2008)

Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
by: Yo Han Lee, et al.
Published: (2021-12-01)

The role of A268V exon-7 polymorphism of PPARA in development of axial spondyloarthritis
by: Akbulut Ekrem, et al.
Published: (2021-07-01)

D-Linking And The Inability Of Subjects In English To Topicalise
by: Georgios Ioannou
Published: (2013-06-01)

L66S F667 (2-14) [fotograf udara]

CBFA2T3 Is PPARA Sensitive and Attenuates Fasting-Induced Lipid Accumulation in Mouse Liver
by: Donghwan Kim, et al.
Published: (2024-05-01)

Activation of HIF1α rescues the hypoxic response and reverses metabolic dysfunction in the diabetic heart
by: da Luz Sousa Fialho, M, et al.
Published: (2021)

Proteomics of Vitreous Humor Reveals PPARA, RXR, and LXR Are Possible Upstream Regulators of Proliferative Diabetic Retinopathy
by: Siyan Li, et al.
Published: (2021-08-01)

Inability to accept defeat in election a trait of dictatorship
by: New Sarawak, Tribune
Published: (2016)

Inability to walk: a rare presentation of Crohn’s disease
by: Elmer Hoekstra, et al.
Published: (2020-12-01)

Inability of Self-expression in the Selected Works of Eliot and Anderson
by: Denis Kuzmanović
Published: (2019-01-01)

The Integration Theory and the Inability to Study Actorness: Change on the Horizon?
by: Petr Kratochvíl
Published: (2011-12-01)

Perceptions of the bearers of HIV/AIDS before the inability to breastfeeding
by: Jucimar Frigo, et al.
Published: (2014-03-01)