Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer.

The functional role of bone morphogenetic protein (BMP) signalling in colorectal cancer (CRC) is poorly defined, with contradictory results in cancer cell line models reflecting the inherent difficulties of assessing a signalling pathway that is context-dependent and subject to genetic constraints....

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Main Authors: Irshad, S, Bansal, M, Guarnieri, P, Davis, H, Al Haj Zen, A, Baran, B, Pinna, C, Rahman, H, Biswas, S, Bardella, C, Jeffery, R, Wang, L, East, J, Tomlinson, I, Lewis, A, Leedham, S
格式: Journal article
語言:English
出版: Wiley 2017