Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria.

Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria.

BACKGROUND: Currently, population pharmacokinetic (PK) studies of anti-malarial drugs are designed primarily by the logistical and ethical constraints of taking blood samples from patients, and the statistical models that are fitted to the data are not formally considered. This could lead to impreci...

书目详细资料
Main Authors:	Jamsen, K, Duffull, S, Tarning, J, Lindegardh, N, White, N, Simpson, J
格式:	Journal article
语言:	English
出版:	BioMed Central 2011

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