The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo

The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo

Limited data exists regarding the combination of Hedgehog signaling (Hh) inhibition and radiotherapy, even though there are several indications that this might be a promising treatment strategy. In this study, we evaluated the combination of two Hh inhibitors, the SMO inhibitor GDC-0449 and the GLI...

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Bibliografiske detaljer
Main Authors:	Gonnissen, A, Isebaert, S, McKee, C, Dok, R, Haustermans, K, Muschel, R
Format:	Journal article
Sprog:	English
Udgivet:	Impact Journals 2016

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