Length-independent structural similarities enrich the antibody CDR canonical class model

Complementarity-determining regions (CDRs) are antibody loops that make up the antigen binding site. Here, we show that all CDR types have structurally similar loops of different lengths. Based on these findings, we created length-independent canonical classes for the non-H3 CDRs. Our length variabl...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Nowak, J, Baker, T, Georges, G, Kelm, S, Klostermann, S, Shi, J, Sridharan, S, Deane, C
स्वरूप: Journal article
भाषा:English
प्रकाशित: Taylor and Francis 2016