Length-independent structural similarities enrich the antibody CDR canonical class model

Complementarity-determining regions (CDRs) are antibody loops that make up the antigen binding site. Here, we show that all CDR types have structurally similar loops of different lengths. Based on these findings, we created length-independent canonical classes for the non-H3 CDRs. Our length variabl...

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書目詳細資料
Main Authors: Nowak, J, Baker, T, Georges, G, Kelm, S, Klostermann, S, Shi, J, Sridharan, S, Deane, C
格式: Journal article
語言:English
出版: Taylor and Francis 2016