Variational Bayes inference of spatial mixture models for segmentation.

Mixture models are commonly used in the statistical segmentation of images. For example, they can be used for the segmentation of structural medical images into different matter types, or of statistical parametric maps into activating and nonactivating brain regions in functional imaging. Spatial mi...

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Main Authors: Woolrich, M, Behrens, T
Format: Journal article
Language:English
Published: 2006
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author Woolrich, M
Behrens, T
author_facet Woolrich, M
Behrens, T
author_sort Woolrich, M
collection OXFORD
description Mixture models are commonly used in the statistical segmentation of images. For example, they can be used for the segmentation of structural medical images into different matter types, or of statistical parametric maps into activating and nonactivating brain regions in functional imaging. Spatial mixture models have been developed to augment histogram information with spatial regularization using Markov random fields (MRFs). In previous work, an approximate model was developed to allow adaptive determination of the parameter controlling the strength of spatial regularization. Inference was performed using Markov Chain Monte Carlo (MCMC) sampling. However, this approach is prohibitively slow for large datasets. In this work, a more efficient inference approach is presented. This combines a variational Bayes approximation with a second-order Taylor expansion of the components of the posterior distribution, which would otherwise be intractable to Variational Bayes. This provides inference on fully adaptive spatial mixture models an order of magnitude faster than MCMC. We examine the behavior of this approach when applied to artificial data with different spatial characteristics, and to functional magnetic resonance imaging statistical parametric maps.
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spelling oxford-uuid:8a6057fe-daa2-4743-991e-e49c0aadf3272022-03-26T22:31:05ZVariational Bayes inference of spatial mixture models for segmentation.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8a6057fe-daa2-4743-991e-e49c0aadf327EnglishSymplectic Elements at Oxford2006Woolrich, MBehrens, TMixture models are commonly used in the statistical segmentation of images. For example, they can be used for the segmentation of structural medical images into different matter types, or of statistical parametric maps into activating and nonactivating brain regions in functional imaging. Spatial mixture models have been developed to augment histogram information with spatial regularization using Markov random fields (MRFs). In previous work, an approximate model was developed to allow adaptive determination of the parameter controlling the strength of spatial regularization. Inference was performed using Markov Chain Monte Carlo (MCMC) sampling. However, this approach is prohibitively slow for large datasets. In this work, a more efficient inference approach is presented. This combines a variational Bayes approximation with a second-order Taylor expansion of the components of the posterior distribution, which would otherwise be intractable to Variational Bayes. This provides inference on fully adaptive spatial mixture models an order of magnitude faster than MCMC. We examine the behavior of this approach when applied to artificial data with different spatial characteristics, and to functional magnetic resonance imaging statistical parametric maps.
spellingShingle Woolrich, M
Behrens, T
Variational Bayes inference of spatial mixture models for segmentation.
title Variational Bayes inference of spatial mixture models for segmentation.
title_full Variational Bayes inference of spatial mixture models for segmentation.
title_fullStr Variational Bayes inference of spatial mixture models for segmentation.
title_full_unstemmed Variational Bayes inference of spatial mixture models for segmentation.
title_short Variational Bayes inference of spatial mixture models for segmentation.
title_sort variational bayes inference of spatial mixture models for segmentation
work_keys_str_mv AT woolrichm variationalbayesinferenceofspatialmixturemodelsforsegmentation
AT behrenst variationalbayesinferenceofspatialmixturemodelsforsegmentation