Effective targeting of the tumor microenvironment for cancer therapy.

BACKGROUND: The tumor microenvironment is an emerging source of novel therapeutic targets in cancer. The glycosaminoglycan hyaluronan (HA) accumulates in 20-30% of tumors and is often associated with poor prognosis. MATERIALS AND METHODS: We developed a digitized, semiquantitative scoring system fo...

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Detalles Bibliográficos
Autores principales: Jiang, P, Li, X, Thompson, C, Huang, Z, Araiza, F, Osgood, R, Wei, G, Feldmann, M, Frost, G, Shepard, H
Formato: Journal article
Lenguaje:English
Publicado: 2012