MHC transmission: insights into gender bias in MS susceptibility.

MHC transmission: insights into gender bias in MS susceptibility.

OBJECTIVE: Major histocompatibility complex (MHC) genes dominate genetic susceptibility factors in multiple sclerosis (MS). Given the general consensus that incidence and prevalence of MS has been rising and specifically in women, we evaluated MHC-gender interactions. METHODS: In a large family-bas...

Full description

Bibliographic Details
Main Authors:	Chao, M, Ramagopalan, S, Herrera, B, Orton, S, Handunnetthi, L, Lincoln, MR, Dyment, D, Sadovnick, A, Ebers, G
Format:	Journal article
Language:	English
Published:	2011

Similar Items

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium.
by: Chao, M, et al.
Published: (2007)

Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
by: Ramagopalan, S, et al.
Published: (2009)

Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis
by: Ramagopalan, S, et al.
Published: (2008)

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium
by: Chao, M, et al.
Published: (2007)

HLA B*44: protective effects in MS susceptibility and MRI outcome measures.
by: Chao, M, et al.
Published: (2011)

Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance.
by: Dyment, D, et al.
Published: (2005)

Parent-of-origin effects in MS: observations from avuncular pairs.
by: Herrera, B, et al.
Published: (2008)

Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility.
by: Lincoln, MR, et al.
Published: (2009)

Parental transmission of MS in a population-based Canadian cohort.
by: Herrera, B, et al.
Published: (2007)

Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex.
by: Chao, M, et al.
Published: (2009)

Expression of the multiple sclerosis associated MHC class II allele HLA-DRBI*1501 is regulated by vitamin D
by: Ebers, G, et al.
Published: (2008)

Epistasis among HLA-DRB1, HLA-DQA1 and HLA-DQB1 Loci Determines Multiple Sclerosis Susceptibility
by: Lincoln, MR, et al.
Published: (2009)

Parental transmission of HLA-DRB1*15 in multiple sclerosis.
by: Ramagopalan, S, et al.
Published: (2008)

Parental non-inherited HLA resistance alleles do not confer protection against multiple sclerosis.
by: Ramagopalan, S, et al.
Published: (2008)

Expression of the multiple sclerosis associated MHC class II allele HLA-DRB1*1501 is regulated by vitamin D
by: Ebers, G, et al.
Published: (2008)

Prenatal, perinatal and early life factors in MS susceptibility
by: Ramagopalan, S, et al.
Published: (2009)

Multiple sclerosis susceptibility and the X chromosome.
by: Herrera, B, et al.
Published: (2007)

Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex
by: Chao, M, et al.
Published: (2009)

Vitamin-D Receptor and 1-alpha-hydroxylase Genes in Risk and Outcome of Multiple Sclerosis in Canadians
by: Orton, S, et al.
Published: (2010)

The MHC and multiple sclerosis susceptibility - several levels of complexity
by: Ebers, G, et al.
Published: (2004)

Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.
by: Sreeram V Ramagopalan, et al.
Published: (2009-02-01)

Fine Mapping of Epigenetic Modifications in Multiple Sclerosis Susceptibility
by: Chao, M, et al.
Published: (2009)

Follow-up investigation of 12 proposed linkage regions in multiple sclerosis.
by: Herrera, B, et al.
Published: (2006)

HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility.
by: Chao, M, et al.
Published: (2008)

The inheritance of resistance alleles in multiple sclerosis.
by: Ramagopalan, S, et al.
Published: (2007)

Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians.
by: Orton, S, et al.
Published: (2011)

Variants in ST8SIA1 do not play a major role in susceptibility to multiple sclerosis in Canadian families.
by: Ramagopalan, S, et al.
Published: (2009)

Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis
by: Lincoln Matthew R, et al.
Published: (2008-07-01)

Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians
by: Orton, S, et al.
Published: (2011)

The role of hereditary spastic paraplegia related genes in multiple sclerosis. A study of disease susceptibility and clinical outcome.
by: DeLuca, G, et al.
Published: (2007)

Effect of immigration on multiple sclerosis sex ratio in Canada: the Canadian Collaborative Study.
by: Orton, S, et al.
Published: (2010)

Mother-child blood group incompatibility and the risk of multiple sclerosis.
by: Ramagopalan, S, et al.
Published: (2010)

Childhood cow's milk allergy and the risk of multiple sclerosis: a population based study
by: Ramagopalan, S, et al.
Published: (2010)

Childhood cow's milk allergy and the risk of multiple sclerosis: a population based study.
by: Ramagopalan, S, et al.
Published: (2010)

Parent-of-origin effect in multiple sclerosis: observations from interracial matings.
by: Ramagopalan, S, et al.
Published: (2009)

Gestational diabetes and multiple sclerosis.
by: Ramagopalan, S, et al.
Published: (2009)

Re: HLA-DRB1 and multiple sclerosis in Malta.
by: Ramagopalan, S, et al.
Published: (2008)

Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis.
by: Chao, M, et al.
Published: (2010)

Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis.
by: Orton, S, et al.
Published: (2008)

Prevalence of MS in Iranian immigrants to British Columbia, Canada.
by: Guimond, C, et al.
Published: (2010)