norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis

norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis

<strong>Background & Aim</strong> Primary sclerosing cholangitis (PSC) represents a devastating bile duct disease, currently lacking effective medical therapy. 24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestat...

Full description

Bibliographic Details
Main Authors:	Fickert, P, Hirschfield, G, Denk, G, Marschall, H, Altorjay, I, Färkkilä, M, Schramm, C, Spengler, U, Chapman, R, Bergquist, A, Schrumpf, E, Nevens, F, Trivedi, P, Reiter, F, Tornai, I, Halilbasic, E, Greinwald, R, Pröls, M, Manns, M, Trauner, M, European Psc Norudca Study Group
Format:	Journal article
Language:	English
Published:	Elsevier 2017

Similar Items

Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice
by: Jennifer K. Truong, et al.
Published: (2023-03-01)

Is ursodeoxycholic acid effective for intrahepatic cholestasis of pregnancy?
by: Sebastián Sepúlveda Marín, et al.
Published: (2016-04-01)

Ursodeoxycholic acid in neonatal sepsis-associated cholestasis
by: Rita Mey Rina, et al.
Published: (2014-08-01)

Ursodeoxycholic acid for treatment of cholestasis in patients with hepatic amyloidosis
by: Faust Dominik, et al.
Published: (2009-01-01)

Efficacy and safety of ursodeoxycholic acid in patients with intrahepatic cholestasis of pregnancy
by: Antonin Parízek, et al.
Published: (2016-09-01)

24-Norursodeoxycholic acid ameliorates experimental alcohol-related liver disease and activates hepatic PPARγ
by: Christoph Grander, et al.
Published: (2023-11-01)

Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis.
by: Oladipupo Adeyemi, et al.
Published: (2017-01-01)

The reversed feto-maternal bile acid gradient in intrahepatic cholestasis of pregnancy is corrected by ursodeoxycholic acid.
by: Victoria Geenes, et al.
Published: (2014-01-01)

Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit
by: Tamorah Lewis, et al.
Published: (2018-06-01)

Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis
by: Briley Annette, et al.
Published: (2009-05-01)

Obstetric Cholestasis: Comparison of Maternal and Perinatal Outcome of Ursodeoxycholic Acid versus Placebo
by: Faiza Safdar, et al.
Published: (2020-03-01)

Efficacy and safety of ursodeoxycholic acid in children with cholestasis: A systematic review and meta-analysis
by: Liang Huang, et al.
Published: (2023-01-01)

Ursodeoxycholic acid to reduce adverse perinatal outcomes for intrahepatic cholestasis of pregnancy: the PITCHES RCT
by: Lucy C Chappell, et al.
Published: (2020-12-01)

Effects of ursodeoxycholic acid and glutathione combination in spleen TNF-α and apoptotic index in rats with cholestasis
by: Danu Darmawan, et al.
Published: (2023-08-01)

Combination of Ursodeoxycholic Acid and Glutathione Improves Intestinal Morphology in Cholestasis by Downregulating TNF-α Expression
by: Jonathan Alvin Nugraha Halim, et al.
Published: (2022-12-01)

Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial.
by: Chappell, L, et al.
Published: (2019)

Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): A randomized controlled trial
by: Chappell, LC, et al.
Published: (2020)

Gradual dosing of ursodeoxycholic acid in mothers with intrahepatic cholestasis of pregnancy may improve composite neonatal outcome
by: Amir Hamud, et al.
Published: (2024-05-01)

A Clinical & Experimental Obstetrics and Gynecology survey on ursodeoxycholic treatment of intrahepatic cholestasis of pregnancy: scholars’ opinion
by: Caroline Ovadia, et al.
Published: (2021-12-01)

Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue.
by: Boberg, K, et al.
Published: (2011)

Hypercortisolism in patients with cholestasis is associated with disease severity
by: Verena Theiler-Schwetz, et al.
Published: (2021-12-01)

Recent advances in understanding and managing cholestasis [version 1; referees: 2 approved]
by: Martin Wagner, et al.
Published: (2016-04-01)

High doses of ursodeoxycholic acid up-regulate the expression of placental breast cancer resistance protein in patients affected by intrahepatic cholestasis of pregnancy.
by: Francesco Azzaroli, et al.
Published: (2013-01-01)

Ursodeoxycholic acid versus placebo in the treatment of women with intrahepatic cholestasis of pregnancy (ICP) to improve perinatal outcomes: protocol for a randomised controlled trial (PITCHES)
by: Chappell, L, et al.
Published: (2018)

STATINS AND URSODEOXYCHOLIC ACID: COOPERATION OR NEUTRALITY?
by: I. N. Grigorieva, et al.
Published: (2016-01-01)

STATINS AND URSODEOXYCHOLIC ACID: COOPERATION OR NEUTRALITY?
by: I. N. Grigorieva, et al.
Published: (2016-01-01)

Transcriptional regulation of hepatobiliary transport systems in health and disease: Implications for a rationale approach to the treatment of intrahepatic cholestasis
by: Martin Wagner, et al.
Published: (2005-04-01)

A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy: the TURRIFIC randomised trial
by: William M. Hague, et al.
Published: (2021-01-01)

P-82 URSODEOXYCHOLIC ACID AND/OR CIPROFIBRATE FOR TREATING PATIENTS WITH PRESUMPTIVE DIAGNOSIS OF LOW PHOSPHOLIPID CHOLELITHIASIS, A CLINICAL SPECTRUM OF PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS TYPE 3
by: Fernanda Linahres, et al.
Published: (2021-09-01)

Ursodeoxycholic acid and cancer prevention
by: A. R. Reyzis
Published: (2019-10-01)

Pleiotropic effects of ursodeoxycholic acid
by: Yu.М. Stepanov, et al.
Published: (2021-06-01)

Biological synthesis of ursodeoxycholic acid
by: Peng Song, et al.
Published: (2023-02-01)

Radioimmunoassay of ursodeoxycholic acid in serum.
by: I Makino, et al.
Published: (1978-05-01)

Primary sclerosing cholangitis – The arteriosclerosis of the bile duct?
by: Trauner Michael, et al.
Published: (2007-01-01)

Histological demonstration of BSEP/ABCB11 inhibition in transient neonatal cholestasis: a case report
by: Anna Baghdasaryan, et al.
Published: (2020-07-01)

Ursodeoxycholic acid: A therapeutic niche in an internist’s practice
by: O M Drapkina, et al.
Published: (2015-04-01)

Polynosological effects of ursodeoxycholic acid (UDCA). Practice of using
by: V. M. Makhov, et al.
Published: (2016-12-01)

Glycochenodeoxycholate Promotes Liver Fibrosis in Mice with Hepatocellular Cholestasis
by: Simon Hohenester, et al.
Published: (2020-01-01)

Use of ursodeoxycholic acid in patients with hypertransaminasemia
by: Claudio Puoti, et al.
Published: (2014-09-01)

The effect of ursodeoxycholic acid in cystic cholangiopathies
by: Frank Lammert, et al.
Published: (2016-11-01)