How is alpha‐synuclein cleared from the cell?
The levels and conformers of alpha‐synuclein are critical in the pathogenesis of Parkinson's Disease and related synucleinopathies. Homeostatic mechanisms in protein degradation and secretion have been identified as regulators of alpha‐synuclein at different stages of its intracellular traffick...
Main Authors: | Stefanis, L, Emmanouilidou, E, Pantazopoulou, M, Kirik, D, Vekrellis, K, Tofaris, GK |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Wiley
2019
|
Similar Items
-
Voltage-Gated Calcium Channels and α-Synuclein: Implications in Parkinson’s Disease
by: Emmanouela Leandrou, et al.
Published: (2019-10-01) -
Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy.
by: Maria Xilouri, et al.
Published: (2009-01-01) -
Intrastriatal Administration of Exosome-Associated Pathological Alpha-Synuclein Is Not Sufficient by Itself to Cause Pathology Transmission
by: Mantia Karampetsou, et al.
Published: (2020-04-01) -
Physiological and pathological properties of alpha-synuclein.
by: Tofaris, G, et al.
Published: (2007) -
Initiation and progression of α-synuclein pathology in Parkinson’s disease
by: Tofaris, GK
Published: (2022)