Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study
Early neurological deterioration (END) is progressive neurological deterioration with an increase in NIHSS score of 2 points or more in the first 72 hours from the onset of acute ischemic stroke. END increases the risk of poor clinical outcomes at day 90 of ischemic stroke. We will study the frequen...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2024
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| _version_ | 1826313592255807488 |
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| author | Nguyen, DT Mai, TD Dao, PV Ha, HT Le, AT Nguyen, TTT Vuong, TX Tran, MC |
| author_facet | Nguyen, DT Mai, TD Dao, PV Ha, HT Le, AT Nguyen, TTT Vuong, TX Tran, MC |
| author_sort | Nguyen, DT |
| collection | OXFORD |
| description | Early neurological deterioration (END) is progressive neurological deterioration with an increase in NIHSS score of 2 points or more in the first 72 hours from the onset of acute ischemic stroke. END increases the risk of poor clinical outcomes at day 90 of ischemic stroke. We will study the frequency, predictors, and outcomes of patients with END in a case-control study at a comprehensive stroke centre in Vietnam. of the design is a descriptive observational study, longitudinal follow-up of patients with minor stroke hospitalized at the Stroke Center of Bach Mai Hospital from December 1, 2023, to December 1, 2024. Minor stroke patients characterized by NIHSS score ≤ 5 hospitalized within 24 hours of symptom onset will be recruited. The estimated END rate is about 30%, relative accuracy ε = 0.11, 95% reliability, expected 5% of patients lost data or follow-up, and an estimated sample size of 779 patients. This study will help determine the END rate in patients with minor stroke and related factors, thereby building a prognostic model for END. Our study determined the END rate in patients with minor stroke in Vietnam and also proposed risk factors for minor stroke management and treatment. |
| first_indexed | 2024-09-25T04:17:23Z |
| format | Journal article |
| id | oxford-uuid:8a9a8455-e443-43cb-b184-c9b8aec975b2 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-09-25T04:17:23Z |
| publishDate | 2024 |
| publisher | Public Library of Science |
| record_format | dspace |
| spelling | oxford-uuid:8a9a8455-e443-43cb-b184-c9b8aec975b22024-07-20T15:26:54ZStudy protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8a9a8455-e443-43cb-b184-c9b8aec975b2EnglishJisc Publications RouterPublic Library of Science2024Nguyen, DTMai, TDDao, PVHa, HTLe, ATNguyen, TTTVuong, TXTran, MCEarly neurological deterioration (END) is progressive neurological deterioration with an increase in NIHSS score of 2 points or more in the first 72 hours from the onset of acute ischemic stroke. END increases the risk of poor clinical outcomes at day 90 of ischemic stroke. We will study the frequency, predictors, and outcomes of patients with END in a case-control study at a comprehensive stroke centre in Vietnam. of the design is a descriptive observational study, longitudinal follow-up of patients with minor stroke hospitalized at the Stroke Center of Bach Mai Hospital from December 1, 2023, to December 1, 2024. Minor stroke patients characterized by NIHSS score ≤ 5 hospitalized within 24 hours of symptom onset will be recruited. The estimated END rate is about 30%, relative accuracy ε = 0.11, 95% reliability, expected 5% of patients lost data or follow-up, and an estimated sample size of 779 patients. This study will help determine the END rate in patients with minor stroke and related factors, thereby building a prognostic model for END. Our study determined the END rate in patients with minor stroke in Vietnam and also proposed risk factors for minor stroke management and treatment. |
| spellingShingle | Nguyen, DT Mai, TD Dao, PV Ha, HT Le, AT Nguyen, TTT Vuong, TX Tran, MC Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study |
| title | Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study |
| title_full | Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study |
| title_fullStr | Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study |
| title_full_unstemmed | Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study |
| title_short | Study protocol: Early neurological deterioration in patients with minor stroke, frequency, predictors, and outcomes in Vietnam single-centre study |
| title_sort | study protocol early neurological deterioration in patients with minor stroke frequency predictors and outcomes in vietnam single centre study |
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