The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression
<p><strong>Objectives</strong> To identify the functional basis for the genetic association of single nucleotide polymorphisms (SNP), upstream of the RUNX3 promoter, with ankylosing spondylitis (AS).</p> <p><strong>Methods</strong> We performed conditional...
Автори: | Vecellio, M, Roberts, AR, Cohen, CJ, Cortes, A, Knight, JC, Bowness, P, Wordsworth, BP |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
BMJ Publishing Group
2015
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