Recognition of shorter and longer trimethyllysine analogues by epigenetic reader proteins

Histone Nε-lysine methylation is a widespread posttranslational modification that is specifically recognised by a diverse class of Nε-methyllysine binding reader proteins. Combined thermodynamic data, molecular dynamics simulations, and quantum chemical studies reveal that reader proteins efficientl...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Al Temimi, A, Belle, R, Kumar, K, Poater, J, Betlem, P, Pieters, B, Paton, R, Bickelhaupt, F, Mecinović, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Royal Society of Chemistry 2018