O'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey.
O'nyong-nyong (ONN) fever, an acute, nonfatal illness characterized by polyarthralgia, is caused by infection with a mosquito-borne central African alphavirus. During 1996-1997, south-central Uganda experienced the second ONN fever epidemic ever recognized. During January and early February 199...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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| _version_ | 1797080752895033344 |
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| author | Sanders, E Rwaguma, E Kawamata, J Kiwanuka, N Lutwama, J Ssengooba, F Lamunu, M Najjemba, R Were, W Bagambisa, G Campbell, G |
| author_facet | Sanders, E Rwaguma, E Kawamata, J Kiwanuka, N Lutwama, J Ssengooba, F Lamunu, M Najjemba, R Were, W Bagambisa, G Campbell, G |
| author_sort | Sanders, E |
| collection | OXFORD |
| description | O'nyong-nyong (ONN) fever, an acute, nonfatal illness characterized by polyarthralgia, is caused by infection with a mosquito-borne central African alphavirus. During 1996-1997, south-central Uganda experienced the second ONN fever epidemic ever recognized. During January and early February 1997, active case-finding and a household cluster serosurvey were conducted in two affected and two comparison areas. A confirmed case was defined as an acute febrile illness with polyarthralgia occurring within the previous 9 months plus serologic confirmation or isolation of ONN virus from blood. In affected (n=129) and comparison (n=115) areas, the estimated infection rates were 45% and 3%, respectively, and the estimated attack rates were 29% and 0%, respectively, for an apparent:inapparent infection ratio of nearly 2 in affected areas. In villages sampled near Lake Kijanebalola, Rakai District, the estimated infection and attack rates were 68% and 41%, respectively, and 55% of sampled households had >/=1 case of ONN fever. In conclusion, this epidemic was focused near lakes and swamps, where it was associated with high infection and attack rates. |
| first_indexed | 2024-03-07T01:04:40Z |
| format | Journal article |
| id | oxford-uuid:8aebdf2e-e98b-4f70-9ef5-16d67b352260 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:04:40Z |
| publishDate | 1999 |
| record_format | dspace |
| spelling | oxford-uuid:8aebdf2e-e98b-4f70-9ef5-16d67b3522602022-03-26T22:34:41ZO'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8aebdf2e-e98b-4f70-9ef5-16d67b352260EnglishSymplectic Elements at Oxford1999Sanders, ERwaguma, EKawamata, JKiwanuka, NLutwama, JSsengooba, FLamunu, MNajjemba, RWere, WBagambisa, GCampbell, GO'nyong-nyong (ONN) fever, an acute, nonfatal illness characterized by polyarthralgia, is caused by infection with a mosquito-borne central African alphavirus. During 1996-1997, south-central Uganda experienced the second ONN fever epidemic ever recognized. During January and early February 1997, active case-finding and a household cluster serosurvey were conducted in two affected and two comparison areas. A confirmed case was defined as an acute febrile illness with polyarthralgia occurring within the previous 9 months plus serologic confirmation or isolation of ONN virus from blood. In affected (n=129) and comparison (n=115) areas, the estimated infection rates were 45% and 3%, respectively, and the estimated attack rates were 29% and 0%, respectively, for an apparent:inapparent infection ratio of nearly 2 in affected areas. In villages sampled near Lake Kijanebalola, Rakai District, the estimated infection and attack rates were 68% and 41%, respectively, and 55% of sampled households had >/=1 case of ONN fever. In conclusion, this epidemic was focused near lakes and swamps, where it was associated with high infection and attack rates. |
| spellingShingle | Sanders, E Rwaguma, E Kawamata, J Kiwanuka, N Lutwama, J Ssengooba, F Lamunu, M Najjemba, R Were, W Bagambisa, G Campbell, G O'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey. |
| title | O'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey. |
| title_full | O'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey. |
| title_fullStr | O'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey. |
| title_full_unstemmed | O'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey. |
| title_short | O'nyong-nyong fever in south-central Uganda, 1996-1997: description of the epidemic and results of a household-based seroprevalence survey. |
| title_sort | o nyong nyong fever in south central uganda 1996 1997 description of the epidemic and results of a household based seroprevalence survey |
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