Exploring neuroinflammatory processes in a mouse model of amyotrophic lateral sclerosis

Exploring neuroinflammatory processes in a mouse model of amyotrophic lateral sclerosis

<p>Amyotrophic lateral sclerosis (ALS) is a devastating degenerative disease, affecting both upper and lower motor neurons in the CNS. Around 10% of ALS cases are classed as familial, and around 20% of these are due to a mutation in the gene superoxide dismutase-1 (SOD1). The SOD1G93A mouse is...

Bibliografski detalji
Glavni autori:	Evans, M, Mr Matthew C Evans
Daljnji autori:	Turner, M
Format:	Disertacija
Jezik:	English
Izdano:	2012
Teme:	Neuroscience Biology (medical sciences) Medical Sciences Motor neurone degenerative disease Pathology

Slični predmeti

The genetics of amyotrophic lateral sclerosis
od: Schymick, J
Izdano: (2009)

In vitro transgenic models to elucidate the molecular mechanisms of TDP-43 pathology in amyotrophic lateral sclerosis
od: Mutihac, R
Izdano: (2013)

Unfolded protein responses in models of Motor Neuron Disease
od: Kwok, A
Izdano: (2010)

Investigating TDP43 biological dysfunction through the characterisation of Tardbp ENU mouse mutants: implications for neurodegeneration
od: De Sao Jose Martinho De Oliveira, H, i dr.
Izdano: (2014)

Model systems for exploring new therapeutic interventions and disease mechanisms in spinal muscular atrophies (SMAs)
od: Sleigh, JN
Izdano: (2012)

Molecular mechanisms of OXR1 function
od: Liu, K
Izdano: (2014)

Functional genetic analysis of motor neuron disease
od: Bäumer, D
Izdano: (2010)

Oligonucleotide-based therapies for neuromuscular disease
od: Douglas, A, i dr.
Izdano: (2015)

Functional analysis of the ALS/FTD associated gene FUS using a novel in vitro genomic DNA expression system
od: Thomas, MR
Izdano: (2013)

Allele specific silencing of proteins at the neuromuscular junction
od: Biba, A
Izdano: (2009)

Selective vulnerability of the primary motor cortex in amyotrophic lateral sclerosis
od: Nolan, M
Izdano: (2019)

Investigating mechanisms of TDP-43 toxicity in cellular models of amyotrophic lateral sclerosis
od: Carroll, E
Izdano: (2022)

Approach to study the brain: towards the early detection of neurodegenerative disease
od: Howard, N
Izdano: (2014)

Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model
od: Yeo, Tianrong, i dr.
Izdano: (2022)

Cell targeted phenotyping: understanding molecular genetic mechanisms of C9ORF72 ALS in motor neurons
od: Burley, S
Izdano: (2018)

Functional characterisation of synuclein-based novel genetic mouse models
od: Anwar, S
Izdano: (2011)

Translating ribosome affinity purification from C9orf72-associated amyotrophic lateral sclerosis patient-derived iPSC motor neurons
od: Sathyaprakash, C
Izdano: (2019)

A combined post-mortem magnetic resonance imaging and quantitative histological study of multiple sclerosis pathology
od: Kolasinski, J, i dr.
Izdano: (2012)

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse
od: Isaacs, A, i dr.
Izdano: (2003)

Mouse models for the investigation of MAPT and its role in neurodegenerative disease
od: Wobst, H
Izdano: (2013)

Inflammation and neurovascular changes in amyotrophic lateral sclerosis
od: Evans, M, i dr.
Izdano: (2013)

Modelling of amyotrophic lateral sclerosis (ALS) using induced pluripotent stem cells (iPSC)
od: Ababneh, N
Izdano: (2017)

Non-hydrolytic functions of acetylcholinesterase: the significance of C-terminal peptides
od: Greenfield, S, i dr.
Izdano: (2008)

Adaptive deep brain stimulation for Parkinson's disease: closed loop stimulation for Parkinson's.
od: Little, S
Izdano: (2014)

Effects of age on sleep and consolidation of motor learning
od: Gudberg, C
Izdano: (2013)

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis
od: McMahon, R, i dr.
Izdano: (2011)

Vitamin D metabolic pathway genes and risk of multiple sclerosis in Canadians
od: Orton, S, i dr.
Izdano: (2011)

Computer analysis of visuo spatial neglect in the assessment of stroke : point location test /
od: 300285 Farrah Azlin Alias
Izdano: (2001)

Analisis berkomputer untuk penilaian visuo spatial neglect melalui ujian albert cancellation /
od: 389276 Ahmad Norhisham Wahono
Izdano: (2001)

Analysis of SMN function in development and Nedd4, a putative modifier of Parkinson's disease, in Drosophila melanogaster
od: Davies, S, i dr.
Izdano: (2013)

Functional characterisation of a multiple sclerosis-associated genetic variant
od: Gregory, A
Izdano: (2012)

Amyotrophic lateral sclerosis.
od: Kiernan, M, i dr.
Izdano: (2011)

Combining digital histology with magnetic resonance imaging in amyotrophic lateral sclerosis
od: Huszar, IN
Izdano: (2020)

Mirror neuron systems : the role of mirroring processes in social cognition /
od: Pineda, Jamie A.
Izdano: (2009)

Inflammation and neurovascular changes in amyotrophic lateral sclerosis.
od: Evans, M, i dr.
Izdano: (2013)

Imaging neuroinflammatory processes with USPIO-MRI
od: Brown, AP
Izdano: (2009)

Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex
od: Chao, M, i dr.
Izdano: (2009)

Early life child exposure and the risk of multiple sclerosis: a population based study
od: Ramagopalan, S, i dr.
Izdano: (2011)

Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model
od: Németh, A, i dr.
Izdano: (2013)

Untangling neuroinflammation in amyotrophic lateral sclerosis
od: Thompson, AG, i dr.
Izdano: (2019)