Exploring neuroinflammatory processes in a mouse model of amyotrophic lateral sclerosis
<p>Amyotrophic lateral sclerosis (ALS) is a devastating degenerative disease, affecting both upper and lower motor neurons in the CNS. Around 10% of ALS cases are classed as familial, and around 20% of these are due to a mutation in the gene superoxide dismutase-1 (SOD1). The SOD1G93A mouse is...
Autors principals: | Evans, M, Mr Matthew C Evans |
---|---|
Altres autors: | Turner, M |
Format: | Thesis |
Idioma: | English |
Publicat: |
2012
|
Matèries: |
Ítems similars
-
The genetics of amyotrophic lateral sclerosis
per: Schymick, J
Publicat: (2009) -
In vitro transgenic models to elucidate the molecular mechanisms of TDP-43 pathology in amyotrophic lateral sclerosis
per: Mutihac, R
Publicat: (2013) -
Model systems for exploring new therapeutic interventions and disease mechanisms in spinal muscular atrophies (SMAs)
per: Sleigh, JN
Publicat: (2012) -
Investigating TDP43 biological dysfunction through the characterisation of Tardbp ENU mouse mutants: implications for neurodegeneration
per: De Sao Jose Martinho De Oliveira, H, et al.
Publicat: (2014) -
Molecular mechanisms of OXR1 function
per: Liu, K
Publicat: (2014)