Exploring neuroinflammatory processes in a mouse model of amyotrophic lateral sclerosis

Exploring neuroinflammatory processes in a mouse model of amyotrophic lateral sclerosis

<p>Amyotrophic lateral sclerosis (ALS) is a devastating degenerative disease, affecting both upper and lower motor neurons in the CNS. Around 10% of ALS cases are classed as familial, and around 20% of these are due to a mutation in the gene superoxide dismutase-1 (SOD1). The SOD1G93A mouse is...

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Bibliografiske detaljer
Main Authors:	Evans, M, Mr Matthew C Evans
Andre forfattere:	Turner, M
Format:	Thesis
Sprog:	English
Udgivet:	2012
Fag:	Neuroscience Biology (medical sciences) Medical Sciences Motor neurone degenerative disease Pathology

Lignende værker

The genetics of amyotrophic lateral sclerosis
af: Schymick, J
Udgivet: (2009)

In vitro transgenic models to elucidate the molecular mechanisms of TDP-43 pathology in amyotrophic lateral sclerosis
af: Mutihac, R
Udgivet: (2013)

Model systems for exploring new therapeutic interventions and disease mechanisms in spinal muscular atrophies (SMAs)
af: Sleigh, JN
Udgivet: (2012)

Investigating TDP43 biological dysfunction through the characterisation of Tardbp ENU mouse mutants: implications for neurodegeneration
af: De Sao Jose Martinho De Oliveira, H, et al.
Udgivet: (2014)

Molecular mechanisms of OXR1 function
af: Liu, K
Udgivet: (2014)

Oligonucleotide-based therapies for neuromuscular disease
af: Douglas, A, et al.
Udgivet: (2015)

Functional analysis of the ALS/FTD associated gene FUS using a novel in vitro genomic DNA expression system
af: Thomas, MR
Udgivet: (2013)

The usage and advantages of several common amyotrophic lateral sclerosis animal models
af: Lijun Zhou, et al.
Udgivet: (2024-02-01)

Allele specific silencing of proteins at the neuromuscular junction
af: Biba, A
Udgivet: (2009)

Hydrogen Sulfide Modulates Astrocytic Toxicity in Mouse Spinal Cord Cultures: Implications for Amyotrophic Lateral Sclerosis
af: Susanna De Stefano, et al.
Udgivet: (2024-10-01)

Neuronal Circuit Dysfunction in Amyotrophic Lateral Sclerosis
af: Andrea Salzinger, et al.
Udgivet: (2024-05-01)

Chronological and Biological Aging in Amyotrophic Lateral Sclerosis and the Potential of Senolytic Therapies
af: Anna Roshani Dashtmian, et al.
Udgivet: (2024-05-01)

Unfolded protein responses in models of Motor Neuron Disease
af: Kwok, A
Udgivet: (2010)

Deontological aspects of the amyotrophic lateral sclerosis
af: T. M. Alekseeva, et al.
Udgivet: (2018-01-01)

Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models
af: Carol Milligan, et al.
Udgivet: (2025-01-01)

Mitochondria: A Promising Convergent Target for the Treatment of Amyotrophic Lateral Sclerosis
af: Teresa Cunha-Oliveira, et al.
Udgivet: (2024-01-01)

Mouse models for the investigation of MAPT and its role in neurodegenerative disease
af: Wobst, H
Udgivet: (2013)

Overview of nomenclature and diagnosis of amyotrophic lateral sclerosis
af: Renshi Xu
Udgivet: (2024-12-01)

Staging model for amyotrophic lateral sclerosis in Singapore
af: Yuan Teck Tay, et al.
Udgivet: (2022-07-01)

Approach to study the brain: towards the early detection of neurodegenerative disease
af: Howard, N
Udgivet: (2014)

Edaravone: A new hope for patients with amyotrophic lateral sclerosis
af: Shivangi Garg, et al.
Udgivet: (2019-01-01)

Functional characterisation of synuclein-based novel genetic mouse models
af: Anwar, S
Udgivet: (2011)

An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis
af: J Barney Bryson, et al.
Udgivet: (2024-01-01)

A combined post-mortem magnetic resonance imaging and quantitative histological study of multiple sclerosis pathology
af: Kolasinski, J, et al.
Udgivet: (2012)

A mutation in Af4 is predicted to cause cerebellar ataxia and cataracts in the robotic mouse
af: Isaacs, A, et al.
Udgivet: (2003)

Histaminergic transmission slows progression of amyotrophic lateral sclerosis
af: Savina Apolloni, et al.
Udgivet: (2019-08-01)

Voxel-based morphometry in amyotrophic lateral sclerosis
af: I. S. Bakulin, et al.
Udgivet: (2019-01-01)

Is tracheostomy still an option in amyotrophic lateral sclerosis?
af: Anne-Chantal Heritier-Barras, et al.
Udgivet: (2013-07-01)

Functional characterisation of a multiple sclerosis-associated genetic variant
af: Gregory, A
Udgivet: (2012)

Potential contribution of spinal interneurons to the etiopathogenesis of amyotrophic lateral sclerosis
af: Luca Goffin, et al.
Udgivet: (2024-07-01)

Analysis of SMN function in development and Nedd4, a putative modifier of Parkinson's disease, in Drosophila melanogaster
af: Davies, S, et al.
Udgivet: (2013)

Asymmetry of hippocampal function in mice: left-right differences in memory processing and vulnerability to amyloid beta
af: Shipton, O, et al.
Udgivet: (2014)

Selective vulnerability of the primary motor cortex in amyotrophic lateral sclerosis
af: Nolan, M
Udgivet: (2019)

Functional genetic analysis of motor neuron disease
af: Bäumer, D
Udgivet: (2010)

Amyotrophic Lateral Sclerosis and Myasthenia Gravis: Comorbidities and Differential Diagnosis
af: Ekaterina V. Pervushina, et al.
Udgivet: (2025-01-01)

Network pharmacology of the MPP+ cellular model of Parkinson’s disease
af: Keane, H
Udgivet: (2015)

The Basis of Cognitive and Behavioral Dysfunction in Amyotrophic Lateral Sclerosis
af: Alexander Bampton, et al.
Udgivet: (2024-11-01)

Amyotrophic lateral sclerosis associated with Sjögren’s syndrome: a case report
af: Yihui Lei, et al.
Udgivet: (2024-08-01)

Investigating mechanisms of TDP-43 toxicity in cellular models of amyotrophic lateral sclerosis
af: Carroll, E
Udgivet: (2022)

Time-restricted ketogenic diet in amyotrophic lateral sclerosis: a case study
af: Matthew C. L. Phillips, et al.
Udgivet: (2024-01-01)