DNA interstrand cross-link repair requires replication-fork convergence

<p style="text-align:justify;"> DNA interstrand cross-links (ICLs) prevent strand separation during DNA replication and transcription and therefore are extremely cytotoxic. In metazoans, a major pathway of ICL repair is coupled to DNA replication, and it requires the Fanconi anemia...

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Autors principals: Zhang, J, Dewar, J, Budzowska, M, Motnenko, A, Cohn, M, Walter, J
Format: Journal article
Idioma:English
Publicat: Springer Nature 2015