Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes.

Sequencing PDX1 (insulin promoter factor 1) in 1788 UK individuals found 5% had a low frequency coding variant, but these variants are not associated with Type 2 diabetes.

AIM: Genome-wide association studies have identified >30 common variants associated with Type 2 diabetes (>5% minor allele frequency). These variants have small effects on individual risk and do not account for a large proportion of the heritable component of the disease. Monogenic for...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Edghill, E, Khamis, A, Weedon, M, Walker, M, Hitman, G, McCarthy, M, Owen, K, Ellard, S, T Hattersley, A, Frayling, T
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2011

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