Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.

Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.

Invariant natural killer T (iNKT) cells are powerful immunomodulatory cells that in mice regulate a variety of immune responses, including acute GVHD (aGVHD). However, their clinical relevance and in particular their role in clinical aGVHD are not known. We studied whether peripheral blood stem cell...

Full description

Bibliographic Details
Main Authors:	Chaidos, A, Patterson, S, Szydlo, R, Chaudhry, M, Dazzi, F, Kanfer, E, McDonald, D, Marin, D, Milojkovic, D, Pavlu, J, Davis, J, Rahemtulla, A, Rezvani, K, Goldman, J, Roberts, I, Apperley, J, Karadimitris, A
Format:	Journal article
Language:	English
Published:	American Society for Hematology 2012

Similar Items

Human invariant NKT cells display alloreactivity instructed by invariant TCR-CD1D interaction and killer immunoglobulin receptors
by: Patterson, S, et al.
Published: (2008)

Human invariant NKT cells display alloreactivity instructed by invariant TCR-CD1d interaction and killer Ig receptors
by: Patterson, S, et al.
Published: (2008)

Human invariant NKT cells display alloreactivity instructed by invariant TCR-CD1d interaction and killer Ig receptors.
by: Patterson, S, et al.
Published: (2008)

Escalating-dose HLA-mismatched DLI is safe for the treatment of leukaemia relapse following alemtuzumab-based myeloablative allo-SCT.
by: Innes, A, et al.
Published: (2013)

Invariant Natural Killer T Cells As Suppressors of Graft-versus-Host Disease in Allogeneic Hematopoietic Stem Cell Transplantation
by: Melissa Mavers, et al.
Published: (2017-07-01)

Natural Killer Cells in Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation
by: Robert S. Negrin, et al.
Published: (2017-04-01)

Recipient natural killer cells alter the course of rejection of allogeneic heart grafts in rats.
by: Oliver Beetz, et al.
Published: (2019-01-01)

Fecal Microbiota Transplant Mitigates Adverse Outcomes Seen in Patients Colonized With Multidrug-Resistant Organisms Undergoing Allogeneic Hematopoietic Cell Transplantation
by: Andrew J. Innes, et al.
Published: (2021-08-01)

Chimerism through the activation of invariant natural killer T cells prolongs graft survival after transplantation of induced pluripotent stem cell-derived allogeneic cardiomyocytes.
by: Shohei Yoshida, et al.
Published: (2022-01-01)

Allogeneic hematopoietic cell transplantation, the microbiome, and graft-versus-host disease
by: Yannouck F. van Lier, et al.
Published: (2023-12-01)

Cytotoxicity of Donor Natural Killer Cells to Allo-Reactive T Cells Are Related With Acute Graft-vs.-Host-Disease Following Allogeneic Stem Cell Transplantation
by: Lixia Sheng, et al.
Published: (2020-07-01)

Analysis of Allogeneic and Syngeneic Bone Marrow Stromal Cell Graft Survival in the Spinal Cord
by: Sharon A. Swanger, et al.
Published: (2005-11-01)

Evidence for B Cell Exhaustion in Chronic Graft-versus-Host Disease
by: Ahmad Khoder, et al.
Published: (2018-01-01)

Purinergic Signalling in Allogeneic Haematopoietic Stem Cell Transplantation and Graft-versus-Host Disease
by: Peter Cuthbertson, et al.
Published: (2021-08-01)

Graft conditioning with fluticasone propionate reduces graft‐versus‐host disease upon allogeneic hematopoietic cell transplantation in mice
by: Erika S Varady, et al.
Published: (2023-09-01)

Invariant NKT cells as a platform for CAR immunotherapy and prevention of acute Graft-versus-Host Disease
by: Anastasios Karadimitris, et al.
Published: (2019-06-01)

Prolonged Allogeneic Islet Graft Survival by Protoporphyrins
by: Antonello Pileggi, et al.
Published: (2005-02-01)

ALLOGENEIC BONE GRAFTING MATERIALS – UPDATE OF THE CURRENT SCIENTIFIC STATUS
by: R. Schnettler, et al.
Published: (2017-12-01)

Graft-versus-host disease after allogeneic hematopoietic stem cell transplantation in children
by: Y. V. Skvortsova, et al.
Published: (2016-12-01)

Graft failure in allogeneic hematopoietic stem cell recipients: diagnosis and treatment
by: U. V. Maslikova, et al.
Published: (2022-05-01)

Improved Relapse-Free Survival in Patients With High Natural Killer Cell Doses in Grafts and During Early Immune Reconstitution After Allogeneic Stem Cell Transplantation
by: Lia Minculescu, et al.
Published: (2020-05-01)

Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells.
by: Holger W Auner, et al.
Published: (2013-01-01)

CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells.
by: Hale, G, et al.
Published: (2000)

Intrathymic inoculation of donor B cells induced indefinite prolongation of fully allogeneic cardiac grafts but not islet or skin grafts.
by: Niimi, M, et al.
Published: (2000)

Parvovirus B19‐associated graft failure after allogeneic hematopoietic stem cell transplantation
by: Nabila Rattani, et al.
Published: (2022-01-01)

Human invariant NKT cells are required for effective in vitro alloresponses.
by: Patterson, S, et al.
Published: (2005)

Preemptive Tolerogenic Delivery of Donor Antigens for Permanent Allogeneic Islet Graft Protection
by: Shusen Wang, et al.
Published: (2015-06-01)

Lyophilized allogeneic costal cartilage graft for septorhinoplasty
by: Jin Sup Eom, et al.
Published: (2023-10-01)

Retrospective Outcome Analysis of Allogenic Bone Graft
by: Vikas Maheshwari, et al.

The role of pattern-recognition receptors in Graft-versus-host disease and Graft-versus-leukemia after allogeneic stem cell transplantation
by: Simon eHeidegger, et al.
Published: (2014-07-01)

Natural Killer Cells Promote Kidney Graft Rejection Independently of Cyclosporine A Therapy
by: Muhammad Imtiaz Ashraf, et al.
Published: (2019-09-01)

Correlation of mixed lymphocyte culture with chronic graft-versus-host disease following allogeneic stem cell transplantation
by: J.E.L. Visentainer, et al.
Published: (2002-05-01)

Metabolic Targets for Improvement of Allogeneic Hematopoietic Stem Cell Transplantation and Graft-vs.-Host Disease
by: Natalia M. Tijaro-Ovalle, et al.
Published: (2019-03-01)

Risk factors for graft-versus-host-disease after donor lymphocyte infusion following T-cell depleted allogeneic stem cell transplantation
by: Eva A. S. Koster, et al.
Published: (2024-03-01)

Advances in the understanding of poor graft function following allogeneic hematopoietic stem-cell transplantation
by: Juan Chen, et al.
Published: (2020-08-01)

Long-Term Graft Function after Allogeneic Islet Transplantation
by: Jonathan R. T. Lakey, et al.
Published: (2007-04-01)

Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9.
by: Ding, Y, et al.
Published: (2009)

Helper Innate Lymphoid Cells in Allogenic Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease
by: Linda Quatrini, et al.
Published: (2020-09-01)

Treg suppression of immunity within inflamed allogeneic grafts
by: Hehua Dai, et al.
Published: (2022-08-01)

Multilevel instrumented posterolateral lumbar spine fusion with an allogeneic cellular bone graft
by: John F. Hall, et al.
Published: (2019-11-01)