CNTF gene transfer protects ganglion cells in rat retinae undergoing focal injury and branch vessel occlusion.

Ciliary neurotrophic factor (CNTF) has been shown to protect ganglion cells in a variety of acute ischaemia models. Here we assess the efficacy of local CNTF gene transfer in protecting retinal ganglion cells when there is focal ischaemia combined with interruption of axoplasmic flow. This dual inju...

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Main Authors: Maclaren, R, Buch, P, Smith, A, Balaggan, K, MacNeil, A, Taylor, J, Osborne, N, Ali, R
格式: Journal article
语言:English
出版: 2006