A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models

A novel molecular magnetic resonance imaging agent targeting activated leukocyte cell adhesion molecule as demonstrated in mouse brain metastasis models

Molecular magnetic resonance imaging (MRI) allows visualization of biological processes at the molecular level. Upregulation of endothelial ALCAM (activated leukocyte cell adhesion molecule) is a key element for leukocyte recruitment in neurological disease. The aim of this study, therefore, was to...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Zarghami, N, Soto, MS, Perez-Balderas, F, Khrapitchev, AA, Karali, CS, Johanssen, VA, Ansorge, O, Larkin, JR, Sibson, NR
Natura:	Journal article
Lingua:	English
Pubblicazione:	SAGE Publications 2020

Documenti analoghi

The ambiguity of brain metastasis response to radiotherapy driven by cellular adhesion molecules
di: Soto, M, et al.
Pubblicazione: (2017)

Mouse models of brain metastasis for unravelling tumour progression
di: Soto, MS, et al.
Pubblicazione: (2016)

Functional role of endothelial adhesion molecules in the early stages of brain metastasis.
di: Soto, MS, et al.
Pubblicazione: (2014)

Improved detection of molecularly targeted iron oxide particles in mouse brain using B0 field stabilised high resolution MRI
di: Gilchrist, S, et al.
Pubblicazione: (2020)

Leukocyte Adhesion Molecules in Diabetic Retinopathy
di: Kousuke Noda, et al.
Pubblicazione: (2012-01-01)

Improving delineation of true tumour volume with multimodal MRI in a rat model of brain metastasis
di: Larkin, JR, et al.
Pubblicazione: (2020)

A brain metastasis therapy tweak, for the better? Concomitant stereotactic radiotherapy and molecular-targeted therapy
di: Soto, M, et al.
Pubblicazione: (2017)

STAT3-mediated astrocyte reactivity associated with brain metastasis contributes to neurovascular dysfunction
di: Sarmiento Soto, M, et al.
Pubblicazione: (2020)

Cell adhesion and cytoskeletal molecules in metastasis /
di: Cress, Anne E., et al.
Pubblicazione: (2006)

Influence of ionic and non-ionic radiographic contrast media on leukocyte adhesion molecules
di: Guy L. J. Vermeiren, et al.
Pubblicazione: (2003-01-01)

Cell adhesion molecules involved in the leukocyte recruitment induced by venom of the snake Bothrops jararaca
di: Stella R. Zamuner, et al.
Pubblicazione: (2002-01-01)

The Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Cancer Metastasis
di: Chee Wai Wong, et al.
Pubblicazione: (2012-01-01)

Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles
di: Zarghami, N, et al.
Pubblicazione: (2018)

Microbubbles containing lysolipid enhance ultrasound‐mediated blood–brain barrier breakdown in vivo
di: Vince, O, et al.
Pubblicazione: (2020)

Selective blood-brain barrier permeabilization of brain metastases by a type 1 receptor-selective tumor necrosis factor mutein
di: Munoz Pinto, MF, et al.
Pubblicazione: (2021)

Abstract 1561: Characterization of circulating monocyte infiltration in brain metastasis
di: Economopoulos, V, et al.
Pubblicazione: (2016)

A patient with leukocyte adhesion defect
di: S. K. Gunasekara, et al.
Pubblicazione: (2018-12-01)

The vascular basement membrane as "soil" in brain metastasis.
di: Carbonell, W, et al.
Pubblicazione: (2009)

Basal cell adhesion molecule promotes metastasis‐associated processes in ovarian cancer
di: Suresh Sivakumar, et al.
Pubblicazione: (2023-01-01)

In Vivo PET Detection of Lung Micrometastasis in Mice by Targeting Endothelial VCAM-1 Using a Dual-Contrast PET/MRI Probe
di: Melemenidis, S, et al.
Pubblicazione: (2024)

Leukocyte adhesion: High-speed cells with ABS.
di: Van Der Merwe, P
Pubblicazione: (1999)

The role of fucosylation in leukocyte adhesion deficiency II.
di: Vestweber, D, et al.
Pubblicazione: (2004)

The multifarious role of microglia in brain metastasis
di: Sarmiento Soto, M, et al.
Pubblicazione: (2018)

Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas
di: Zernecke, A, et al.
Pubblicazione: (2020)

Molecular magnetic resonance imaging of acute vascular cell adhesion molecule-1 expression in a mouse model of cerebral ischemia.
di: Hoyte, L, et al.
Pubblicazione: (2010)

Adhesion molecules /
di: Preedy, Victor R.
Pubblicazione: (c201)

Are bloodstream leukocytes Trojan Horses for the metastasis of Staphylococcus aureus?
di: Thwaites, G, et al.
Pubblicazione: (2011)

Post-translational modification-regulated leukocyte adhesion and migration
di: Loh, Jia Tong, et al.
Pubblicazione: (2016)

Leukocyte adhesion deficiency II: therapy and genetic defect.
di: Wild, M, et al.
Pubblicazione: (2002)

Functional role of EMR2 in leukocyte adhesion and spreading
di: Kishore, S, et al.
Pubblicazione: (2005)

Anti-VCAM-1 targeted MRI allows earlier detection of brain metastases in a xenograft melanoma mouse model
di: Cheng, V, et al.
Pubblicazione: (2018)

Mechanistic pathways underlying altered neurovascular coupling in brain metastasis
di: Sarmiento Soto, M, et al.
Pubblicazione: (2016)

Tumor Metastasis to the Liver, and the Roles of Proteinases and Adhesion Molecules: New Concepts from In Vivo Videomicroscopy
di: Alan C Groom, et al.
Pubblicazione: (1999-01-01)

Improved Detection of Molecularly Targeted Iron Oxide Particles in Small Animals with High Resolution MRI
di: Kinchesh, P, et al.
Pubblicazione: (2019)

Intercellular adhesion molecule-4 and CD36 are implicated in the abnormal adhesiveness of sickle cell SAD mouse erythrocytes to endothelium
di: Marie-Marcelle Trinh-Trang-Tan, et al.
Pubblicazione: (2010-05-01)

VCAM-1 targeted magnetic resonance imaging enables detection of brain micrometastases from different primary tumours
di: Cheng, VWT, et al.
Pubblicazione: (2018)

Hematologically important mutations : leukocyte adhesion deficiency (first update)
di: Holland, Steven M., et al.
Pubblicazione: (2013)

Correction of leukocyte adhesion deficiency type II with oral fucose.
di: Marquardt, T, et al.
Pubblicazione: (1999)

Enhancement of PCR-RFLP Typing of Bovine Leukocyte Adhesion Deficiency
di: Attila Zsolnai, et al.
Pubblicazione: (1997-09-01)

Anti-Inflammatory Microglia/Macrophages as a Potential Therapeutic Target in Brain Metastasis
di: Andreou, K, et al.
Pubblicazione: (2017)