Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells.
Significant insight has been gained into constraints on the sensitivity and specificity of staining with class I tetramers. The function of the populations that are defined varies with the clinical situation. Insight has also been gained into the determinants of the CD8(+) T cell response during pri...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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| _version_ | 1826283877707022336 |
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| author | Kelleher, A Rowland-Jones, S |
| author_facet | Kelleher, A Rowland-Jones, S |
| author_sort | Kelleher, A |
| collection | OXFORD |
| description | Significant insight has been gained into constraints on the sensitivity and specificity of staining with class I tetramers. The function of the populations that are defined varies with the clinical situation. Insight has also been gained into the determinants of the CD8(+) T cell response during primary and chronic HIV infection. Human class II tetramers have been synthesised but their role in defining CD4(+) T cell function in HIV infection remains to be determined. |
| first_indexed | 2024-03-07T01:05:27Z |
| format | Journal article |
| id | oxford-uuid:8b2d1f1a-6c9d-4041-b93b-b581b3358cf7 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:05:27Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:8b2d1f1a-6c9d-4041-b93b-b581b3358cf72022-03-26T22:36:25ZFunctions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8b2d1f1a-6c9d-4041-b93b-b581b3358cf7EnglishSymplectic Elements at Oxford2000Kelleher, ARowland-Jones, SSignificant insight has been gained into constraints on the sensitivity and specificity of staining with class I tetramers. The function of the populations that are defined varies with the clinical situation. Insight has also been gained into the determinants of the CD8(+) T cell response during primary and chronic HIV infection. Human class II tetramers have been synthesised but their role in defining CD4(+) T cell function in HIV infection remains to be determined. |
| spellingShingle | Kelleher, A Rowland-Jones, S Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells. |
| title | Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells. |
| title_full | Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells. |
| title_fullStr | Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells. |
| title_full_unstemmed | Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells. |
| title_short | Functions of tetramer-stained HIV-specific CD4(+) and CD8(+) T cells. |
| title_sort | functions of tetramer stained hiv specific cd4 and cd8 t cells |
| work_keys_str_mv | AT kellehera functionsoftetramerstainedhivspecificcd4andcd8tcells AT rowlandjoness functionsoftetramerstainedhivspecificcd4andcd8tcells |