Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo.

While memory T cells are maintained by continuous turnover, it is not clear how human regulatory CD4+ CD45RO+ CD25hi Foxp3+ T lymphocyte populations persist throughout life. We therefore used deuterium labeling of cycling cells in vivo to determine whether these cells could be replenished by prolife...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Vukmanovic-Stejic, M, Zhang, Y, Cook, J, Fletcher, J, McQuaid, A, Masters, J, Rustin, M, Taams, L, Beverley, P, Macallan, D, Akbar, A
פורמט:	Journal article
שפה:	English
יצא לאור:	2006

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo.

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