Comprehensive identification of RNA-binding domains in human cells

Comprehensive identification of RNA-binding domains in human cells

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Mammalian cells harbor more than a thousand RNA-binding proteins (RBPs), with half of these employing unknown modes of RNA binding. We developed RBDmap to determine the RNA-binding sites of native RBPs on a proteome-wide scale. We identified 1174 binding sites within 529 HeLa cell RBPs, discovering...

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Библиографические подробности
Главные авторы:	Castello, A, Fischer, B, Frese, C, Horos, R, Alleaume, A, Foehr, S, Curk, T, Krijgsveld, J, Hentze, M
Формат:	Journal article
Опубликовано:	Cell Press 2016

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