Immunization with recombinant protein: conditions for cytotoxic T cell and/or antibody induction.

Safe vaccines should optimally induce both cell-mediated and humoral immunity. Recently, it has been shown that protective cytotoxic T cells (CTLs) can be induced not only with live vaccines, but also with recombinant viral proteins. This report shows in C57BL/6 (H-2b) mice that the recombinant nucl...

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Bibliographic Details
Main Authors: Bachmann, M, Hengartner, H, Zinkernagel, R
Format: Journal article
Language:English
Published: Springer-Verlag 1994