Randomised controlled trials in primary care: case study.
All trials require a compromise between including sufficient practitioners to recruit a representative cohort of patients and the time and cost of recruiting and maintaining the motivation of these practitioners. Prior beliefs relating to the efficacy and direct or side effects of an intervention af...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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| _version_ | 1797080855595712512 |
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| author | Wilson, S Delaney, B Roalfe, A Roberts, L Redman, V Wearn, A Hobbs, F |
| author_facet | Wilson, S Delaney, B Roalfe, A Roberts, L Redman, V Wearn, A Hobbs, F |
| author_sort | Wilson, S |
| collection | OXFORD |
| description | All trials require a compromise between including sufficient practitioners to recruit a representative cohort of patients and the time and cost of recruiting and maintaining the motivation of these practitioners. Prior beliefs relating to the efficacy and direct or side effects of an intervention affect both doctor and patient participation. Trials in any setting are rarely fully representative with respect to both patient and disease related characteristics. Modelling, sensitivity, analysis, and statistical estimates of uncertainty are necessary to determine the generalisability of trials and to particularise results to a given clinical setting. Trials in primary care should give more representative results and are preferable to applying results obtained in secondary care. |
| first_indexed | 2024-03-07T01:06:12Z |
| format | Journal article |
| id | oxford-uuid:8b6f00d7-3052-4928-9450-4f2a90808bdc |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:06:12Z |
| publishDate | 2000 |
| record_format | dspace |
| spelling | oxford-uuid:8b6f00d7-3052-4928-9450-4f2a90808bdc2022-03-26T22:37:59ZRandomised controlled trials in primary care: case study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8b6f00d7-3052-4928-9450-4f2a90808bdcEnglishSymplectic Elements at Oxford2000Wilson, SDelaney, BRoalfe, ARoberts, LRedman, VWearn, AHobbs, FAll trials require a compromise between including sufficient practitioners to recruit a representative cohort of patients and the time and cost of recruiting and maintaining the motivation of these practitioners. Prior beliefs relating to the efficacy and direct or side effects of an intervention affect both doctor and patient participation. Trials in any setting are rarely fully representative with respect to both patient and disease related characteristics. Modelling, sensitivity, analysis, and statistical estimates of uncertainty are necessary to determine the generalisability of trials and to particularise results to a given clinical setting. Trials in primary care should give more representative results and are preferable to applying results obtained in secondary care. |
| spellingShingle | Wilson, S Delaney, B Roalfe, A Roberts, L Redman, V Wearn, A Hobbs, F Randomised controlled trials in primary care: case study. |
| title | Randomised controlled trials in primary care: case study. |
| title_full | Randomised controlled trials in primary care: case study. |
| title_fullStr | Randomised controlled trials in primary care: case study. |
| title_full_unstemmed | Randomised controlled trials in primary care: case study. |
| title_short | Randomised controlled trials in primary care: case study. |
| title_sort | randomised controlled trials in primary care case study |
| work_keys_str_mv | AT wilsons randomisedcontrolledtrialsinprimarycarecasestudy AT delaneyb randomisedcontrolledtrialsinprimarycarecasestudy AT roalfea randomisedcontrolledtrialsinprimarycarecasestudy AT robertsl randomisedcontrolledtrialsinprimarycarecasestudy AT redmanv randomisedcontrolledtrialsinprimarycarecasestudy AT wearna randomisedcontrolledtrialsinprimarycarecasestudy AT hobbsf randomisedcontrolledtrialsinprimarycarecasestudy |