Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.

CD8 T cells lose the capacity to control HIV infection, but the extent of the impairment of CD8 T-cell functions and the mechanisms that underlie it remain controversial. Here we report an extensive ex vivo analysis of HIV-specific CD8 T cells, covering the expression of 16 different molecules invol...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Ribeiro-dos-Santos, P, Turnbull, E, Monteiro, M, Legrand, A, Conrod, K, Baalwa, J, Pellegrino, P, Shaw, G, Williams, I, Borrow, P, Rocha, B
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2012