Hypoxia and myocardial remodeling in human cardiac allografts: a time-course study.
BACKGROUND: Cardiac allografts are known to develop myocardial fibrosis, which may be a cause of progressive cardiac dysfunction. Apart from the renin-angiotensin and transforming growth factor-beta system, hypoxia has been proposed as an important player in the pathogenesis of fibrosis, but its si...
Main Authors: | Gramley, F, Lorenzen, J, Pezzella, F, Kettering, K, Himmrich, E, Plumhans, C, Koellensperger, E, Munzel, T |
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Format: | Journal article |
Language: | English |
Published: |
2009
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