Definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)

Several carotid plaque characteristics, including a thin fibrous cap, lipid necrotic core and intraplaque haemorrhage, have been suggested as potential markers to select patients at high risk for future stroke. On ultrasound, these “high risk” characteristics appear echolucent. The Asymptomatic Caro...

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Main Authors: Huibers, A, de Borst, G, Bulbulia, R, Halliday, A
Format: Journal article
Published: Elsevier 2015
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author Huibers, A
de Borst, G
Bulbulia, R
Halliday, A
author_facet Huibers, A
de Borst, G
Bulbulia, R
Halliday, A
author_sort Huibers, A
collection OXFORD
description Several carotid plaque characteristics, including a thin fibrous cap, lipid necrotic core and intraplaque haemorrhage, have been suggested as potential markers to select patients at high risk for future stroke. On ultrasound, these “high risk” characteristics appear echolucent. The Asymptomatic Carotid Surgery Trial-1 (ACST-1) is the largest randomised controlled trial comparing carotid endarterectomy (CEA) with deferral of CEA in patients with severe asymptomatic carotid artery stenosis. We aimed to assess whether ultrasound characterized plaque echogenicity was a predictor for ischaemic stroke in asymptomatic patients randomized to deferred treatment in ACST-1.
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spelling oxford-uuid:8bd22e1b-b568-47c4-be5d-741910007e352022-03-26T22:40:37ZDefinite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8bd22e1b-b568-47c4-be5d-741910007e35Symplectic Elements at OxfordElsevier2015Huibers, Ade Borst, GBulbulia, RHalliday, ASeveral carotid plaque characteristics, including a thin fibrous cap, lipid necrotic core and intraplaque haemorrhage, have been suggested as potential markers to select patients at high risk for future stroke. On ultrasound, these “high risk” characteristics appear echolucent. The Asymptomatic Carotid Surgery Trial-1 (ACST-1) is the largest randomised controlled trial comparing carotid endarterectomy (CEA) with deferral of CEA in patients with severe asymptomatic carotid artery stenosis. We aimed to assess whether ultrasound characterized plaque echogenicity was a predictor for ischaemic stroke in asymptomatic patients randomized to deferred treatment in ACST-1.
spellingShingle Huibers, A
de Borst, G
Bulbulia, R
Halliday, A
Definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)
title Definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)
title_full Definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)
title_fullStr Definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)
title_full_unstemmed Definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)
title_short Definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial-1 (ACST-1)
title_sort definite plaque echolucency is sssociated with a higher risk of ipsilateral ischaemic stroke during early follow up in the asymptomatic carotid surgery trial 1 acst 1
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AT deborstg definiteplaqueecholucencyissssociatedwithahigherriskofipsilateralischaemicstrokeduringearlyfollowupintheasymptomaticcarotidsurgerytrial1acst1
AT bulbuliar definiteplaqueecholucencyissssociatedwithahigherriskofipsilateralischaemicstrokeduringearlyfollowupintheasymptomaticcarotidsurgerytrial1acst1
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