The influence of Ras pathway signaling on tumor radiosensitivity.
Radiotherapy is used to treat approximately 60% of solid tumors in the US. The relative radiosensitivity of these tumors can have a significant impact upon local control. One factor that has been shown to contribute to the increased survival of tumor cells is the activation of signaling pathways in...
Main Authors: | Kim, I, Fernandes, A, Gupta, A, Mckenna, W, Bernhard, E |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2004
|
Similar Items
-
Modifying radiosensitivity in tumors: Targeting the Ras-PI-3 kinase pathway.
by: Muschel, R, et al.
Published: (2001) -
The RAS signal transduction pathway and its role in radiation sensitivity.
by: Mckenna, W, et al.
Published: (2003) -
Selective inhibition of Ras, phosphoinositide 3 kinase, and Akt isoforms increases the radiosensitivity of human carcinoma cell lines.
by: Kim, I, et al.
Published: (2005) -
The Ras radiation resistance pathway.
by: Gupta, A, et al.
Published: (2001) -
Dual inhibition of the PI3K/mTOR pathway increases tumor radiosensitivity by normalizing tumor vasculature.
by: Fokas, E, et al.
Published: (2012)