Circulating SFLT-1 is placentally derived in normal pregnancy
Excess hypoxia can lead to developmental abnormalities and antenatal deficits such as fetal intrauterine growth restriction and preeclampsia. Capillary pericytes are multifunctional cells wrapped around the vascular endothelium that play essential roles in vascular development and blood flood regula...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Conference item |
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Elsevier
2018
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| _version_ | 1797080944807510016 |
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| author | Cerdeira, A Kandzija, N Burdujan, A Zhang, W Motta-Mejia, C White, K Gill, M Cooke, W Thammasate, B Ri, R Pargmae, P James, T Redman, C Vatish, M |
| author_facet | Cerdeira, A Kandzija, N Burdujan, A Zhang, W Motta-Mejia, C White, K Gill, M Cooke, W Thammasate, B Ri, R Pargmae, P James, T Redman, C Vatish, M |
| author_sort | Cerdeira, A |
| collection | OXFORD |
| description | Excess hypoxia can lead to developmental abnormalities and antenatal deficits such as fetal intrauterine growth restriction and preeclampsia. Capillary pericytes are multifunctional cells wrapped around the vascular endothelium that play essential roles in vascular development and blood flood regulation. In vivo, brain pericytes respond to hypoxia by irreversibly constricting capillaries and thus causing cell death in rigor. To date, placental capillary pericytes (PLVP) have not been fully characterized in placenta biology. We aimed to investigate the effects of hypoxia on human PLVP. |
| first_indexed | 2024-03-07T01:07:31Z |
| format | Conference item |
| id | oxford-uuid:8bdb8a64-20a0-4091-92eb-fbcf68b6c195 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T01:07:31Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:8bdb8a64-20a0-4091-92eb-fbcf68b6c1952022-03-26T22:40:52ZCirculating SFLT-1 is placentally derived in normal pregnancyConference itemhttp://purl.org/coar/resource_type/c_5794uuid:8bdb8a64-20a0-4091-92eb-fbcf68b6c195Symplectic Elements at OxfordElsevier2018Cerdeira, AKandzija, NBurdujan, AZhang, WMotta-Mejia, CWhite, KGill, MCooke, WThammasate, BRi, RPargmae, PJames, TRedman, CVatish, MExcess hypoxia can lead to developmental abnormalities and antenatal deficits such as fetal intrauterine growth restriction and preeclampsia. Capillary pericytes are multifunctional cells wrapped around the vascular endothelium that play essential roles in vascular development and blood flood regulation. In vivo, brain pericytes respond to hypoxia by irreversibly constricting capillaries and thus causing cell death in rigor. To date, placental capillary pericytes (PLVP) have not been fully characterized in placenta biology. We aimed to investigate the effects of hypoxia on human PLVP. |
| spellingShingle | Cerdeira, A Kandzija, N Burdujan, A Zhang, W Motta-Mejia, C White, K Gill, M Cooke, W Thammasate, B Ri, R Pargmae, P James, T Redman, C Vatish, M Circulating SFLT-1 is placentally derived in normal pregnancy |
| title | Circulating SFLT-1 is placentally derived in normal pregnancy |
| title_full | Circulating SFLT-1 is placentally derived in normal pregnancy |
| title_fullStr | Circulating SFLT-1 is placentally derived in normal pregnancy |
| title_full_unstemmed | Circulating SFLT-1 is placentally derived in normal pregnancy |
| title_short | Circulating SFLT-1 is placentally derived in normal pregnancy |
| title_sort | circulating sflt 1 is placentally derived in normal pregnancy |
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